Introduction to P-Toluenesulfonyl Semicarbazide (RA/TSSC) 10396-10-8

P-Toluenesulfonyl semicarbazide (RA/TSSC) 10396-10-8 is an organic compound made by reacting p-toluenesulfonyl chloride with semicarbazide. This compound serves as a critical reagent in organic chemistry, particularly for the synthesis of semicarbazones, hydrazones, and Schiff bases, which are widely used in pharmaceuticals, agrochemicals, and fine chemical manufacturing. The compound has a white crystalline appearance and is soluble in polar solvents, making it highly suitable for various laboratory and industrial applications.

Chemical Formula: C7H10N2O2S

CAS Number: 10396-10-8

Molecular Structure: P-Toluenesulfonyl semicarbazide consists of a p-toluenesulfonyl group (C6H4CH3SO2) attached to a semicarbazide moiety (NH2-C(NH2)-CO).

Chemical Properties of P-Toluenesulfonyl Semicarbazide (RA/TSSC) 10396-10-8

Solubility: It is soluble in a variety of polar solvents, including methanol, ethanol, and acetone, but is relatively insoluble in non-polar solvents such as hexane.

Stability: The compound is stable under normal conditions and does not decompose easily. However, it should be kept away from strong acids, bases, or reactive agents.

Reactivity: The sulfonyl group in P-Toluenesulfonyl semicarbazide (RA/TSSC) 10396-10-8 is highly reactive and can form various derivatives through nucleophilic substitution reactions. This reactivity is essential for its use in organic synthesis.

Safety Considerations for P-Toluenesulfonyl Semicarbazide (RA/TSSC) 10396-10-8

Toxicity: P-Toluenesulfonyl semicarbazide (RA/TSSC) 10396-10-8 is not highly toxic, but it should still be handled with care. Direct contact with skin and eyes should be avoided, and proper personal protective equipment (PPE) should be worn.

Storage: The compound should be stored in a cool, dry place, away from strong acids or bases to prevent decomposition or undesired reactions.

Ventilation: Ensure adequate ventilation in the workspace, especially when working with the compound in its powdered form, to avoid inhalation of dust particles.