Product Description:

N-Ethyl-p-toluene sulfonamide is a white crystalline solid. It is required to have a minimum purity of 99% and a melting point between 58-62°C. The maximum allowed water content is 0.5%, and the colority (APHA) should not exceed 30 Pt/Co units. The chloride ion content is limited to a maximum of 100 ppm, and the ash content should not exceed 0.2%. The acid value (calculated as KOH) has a maximum limit of 1.6 mg/g.

This chemical is commonly used in various industries and applications. It serves as an important intermediate in organic synthesis and finds wide usage in the production processes of pharmaceuticals, agrochemicals, dyes, and polymers.

N-Ethyl-p-toluene sulfonamide exhibits good solubility in organic solvents and has moderate solubility in water. Its compliance with quality standards ensures its stability and usability in various formulations.

Chemical Properties

Molecular Formula: C9H13NO2S

CAS Number: 2042-53-9

Appearance: Colorless to light yellow liquid or crystalline solid

Melting Point: 62-64°C

Solubility: Soluble in alcohol, chloroform, and other organic solvents

The structure of N-ethyl-p-toluene sulfonamide contributes to its versatility in both research and industrial applications.

Applications of N-Ethyl-p-Toluene Sulfonamide

N-ethyl-p-toluene sulfonamide is used in a variety of fields, including pharmaceuticals, organic synthesis, and agrochemicals. Understanding its key applications can help buyers appreciate its value and understand the importance of securing it at the best price.

Pharmaceutical Industry

Antibiotic Synthesis: Sulfonamide-based drugs are important in the treatment of bacterial infections. N-ethyl-p-toluene sulfonamide derivatives are used to synthesize these antibiotics.

Diuretics: N-ethyl-p-toluene sulfonamide is used in the synthesis of drugs that help manage conditions like hypertension and fluid retention.

Anti-inflammatory Drugs: Sulfonamide derivatives are key in the development of medications that reduce inflammation and pain.

Organic Synthesis

Polymer Production: N-ethyl-p-toluene sulfonamide is used as a monomer in the preparation of specialty polymers, which are widely used in coatings, adhesives, and elastomers.

Heterocyclic Compounds: Sulfonamides, including N-ethyl-p-toluene sulfonamide, are involved in the synthesis of heterocyclic compounds that are important in drug discovery and industrial chemistry.

Agrochemical Applications

Herbicides and Pesticides: Compounds derived from N-ethyl-p-toluene sulfonamide are used to create agrochemicals that protect crops from pests and diseases.

Plant Growth Regulators: N-ethyl-p-toluene sulfonamide derivatives can also serve as plant growth regulators, enhancing crop yields and quality.

Safety and Handling of N-Ethyl-p-Toluene Sulfonamide

Health and Safety Precautions: N-ethyl-p-toluene sulfonamide is generally considered to be of low toxicity. However, it may cause irritation to the skin, eyes, and respiratory system. Personal protective equipment (PPE), such as gloves, goggles, and lab coats, should be worn when handling this chemical. In case of accidental exposure, rinse the affected area with water immediately and seek medical attention if necessary.

Fire and Explosion Hazards: N-ethyl-p-toluene sulfonamide is not highly flammable but should be kept away from open flames or high heat sources. Proper storage in a cool, dry area is recommended to prevent decomposition or other hazardous reactions.

Health and Safety Precautions: Proper disposal of N-ethyl-p-toluene sulfonamide and its derivatives is essential to prevent environmental contamination. Follow local environmental regulations when disposing of waste or excess chemical material.