Product Description:

N-Ethyl-o,p-toluene sulfonamide is a straw yellow transparent liquid. It is required to have a minimum purity of 99%, with a maximum ash content of 0.2% and a maximum water content of 0.3%. The colority (APHA) should not exceed 120 Pt/Co, and the maximum allowed free acid content is 0.1%.

This chemical is commonly used in various industries and applications. It serves as an important intermediate in organic synthesis and finds wide usage in the production processes of pharmaceuticals, agrochemicals, dyes, and polymers.

N-Ethyl-o,p-toluene sulfonamide exhibits good solubility in organic solvents and moderate solubility in water. Its maximum water content of 0.3% ensures its stability and usability in various formulations.

Chemical Formula and Properties

Molecular Formula: C9H13NO2S

CAS Number: Not yet assigned (used in specific research)

Appearance: Colorless to light yellow liquid or solid (depending on the purity)

Melting Point: Typically in the range of 40-45°C

Solubility: Soluble in ethanol, chloroform, and other polar organic solvents; sparingly soluble in water.

The structure of N-ethyl-o,p-toluene sulfonamide contributes to its applications in both chemical synthesis and as a building block in pharmaceutical preparations.

Applications of N-Ethyl-o,p-Toluene Sulfonamide

Pharmaceutical Synthesis

Antibiotics: Many sulfonamide derivatives, including those based on N-ethyl-o,p-toluene sulfonamide, are used in the synthesis of antimicrobial agents, which target bacterial infections by inhibiting folic acid synthesis in bacteria.

Anti-inflammatory Drugs: Due to its anti-inflammatory properties, N-ethyl-o,p-toluene sulfonamide derivatives may be used in the development of drugs to treat conditions like arthritis.

Diuretics: N-ethyl-o,p-toluene sulfonamide and its derivatives can be modified to create drugs that help reduce fluid retention in the body.

Organic Synthesis

Reactions with nucleophiles: The nitrogen in the sulfonamide group can undergo nucleophilic substitution reactions, forming bonds with electrophilic centers in other organic molecules.

Heterocyclic compound synthesis: N-Ethyl-o,p-toluene sulfonamide can be used in the preparation of heterocyclic compounds, which are important in medicinal chemistry and materials science.

Polymer Industry

Coatings and adhesives: Polymers made with N-ethyl-o,p-toluene sulfonamide are used in coatings that require enhanced adhesion and durability.

Elastomers and plastics: The compound's incorporation into polymer chains can improve the flexibility and elasticity of certain plastics, making them suitable for use in automotive, medical, and consumer products.

Agricultural Chemicals

Sulfonamide-based compounds are often used in the production of agrochemicals, including herbicides, fungicides, and insecticides. N-ethyl-o,p-toluene sulfonamide can be modified to create derivatives that possess pesticidal or herbicidal activity. These agrochemicals are crucial for managing crop pests, diseases, and weeds, improving agricultural productivity and sustainability.