• Chemical Identity: TSH, with the CAS number 1576-35-8, is a specialized organic compound widely recognized for its unique structure and utility in chemical synthesis.

• Nomenclature: It is formally known as 2,4,6-Trihydroxyacetophenone or 1-(2,4,6-trihydroxyphenyl)ethanone. The abbreviation TSH is commonly used in scientific and industrial contexts.

• Physical Properties: TSH (1576-35-8) typically appears as a pale yellow crystalline powder. It is soluble in ethanol, acetone, and other polar solvents.

Chemical Structure and Characteristics

• Molecular Formula: The molecular formula of TSH (1576-35-8) is C8H8O4, consisting of a phenolic ring substituted with three hydroxyl groups and a ketone group.

• Molecular Weight: Approximately 168.15 g/mol.

• Functional Groups: The presence of hydroxyl (-OH) groups gives TSH (1576-35-8) strong antioxidant properties and makes it highly reactive in various organic reactions.

• Reactivity: It can undergo oxidation, esterification, and conjugation reactions, making it a versatile intermediate.

Applications of TSH (1576-35-8)

• Pharmaceuticals: TSH (1576-35-8) is used as a precursor in the synthesis of biologically active molecules, including some anticancer and anti-inflammatory agents.

• Cosmetic Industry: Due to its antioxidant properties, TSH is occasionally incorporated into cosmetic formulations to combat oxidative stress.

• Analytical Chemistry: TSH (1576-35-8) is employed as a chelating agent in complexometric titrations and as a reagent in the detection of metal ions.

• Research and Development: It serves as a scaffold for developing various functional molecules in organic synthesis laboratories.

Synthesis and Production of TSH (1576-35-8)

• Precursor Materials: Common synthetic routes start from phloroglucinol and acetylating agents.

• Reaction Conditions: The acetylation process requires careful control of temperature and pH to optimize the yield of TSH (1576-35-8).

• Purification: After synthesis, TSH is purified using recrystallization techniques or chromatography to ensure high purity suitable for industrial use.

Safety and Handling

• Toxicology: TSH (1576-35-8) is considered to have low toxicity but should be handled with care to avoid inhalation or contact with skin and eyes.

• Storage Conditions: It should be stored in a cool, dry place, away from direct sunlight and incompatible substances such as strong oxidizers.

• Protective Equipment: When working with TSH (1576-35-8), appropriate personal protective equipment such as gloves, goggles, and lab coats is recommended.

Environmental Impact and Biodegradability

• Biodegradability: TSH (1576-35-8) is moderately biodegradable and does not pose a significant long-term environmental hazard under proper disposal conditions.

• Disposal: Waste materials containing TSH should be disposed of according to local environmental regulations, typically through incineration or chemical neutralization.

Regulatory and Compliance Aspects

• Global Availability: TSH (1576-35-8) is listed in various chemical registries and can be sourced globally through chemical suppliers.

• Compliance: It complies with REACH regulations in the EU and is approved for use in controlled industrial and research applications.

• MSDS Documentation: Material Safety Data Sheets for TSH (1576-35-8) are readily available and provide detailed safety information for users.